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Ambien is a brand name for the medication zolpidem, which is primarily used to treat insomnia, a sleep disorder characterized by difficulty falling asleep or staying asleep. Ambien is a sedative-hypnotic medication that works by affecting certain chemicals in the brain, particularly gamma-aminobutyric acid (GABA). GABA is a neurotransmitter that helps regulate brain activity, and increasing its activity can induce relaxation and sleep.